Leucovorin Calcium (leucovorin calcium)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Leucovorin calcium is the calcium salt of folinic acid, an active metabolite of folic acid.

USES: This medication is used to treat or prevent serious blood cell disorders (such as thrombocytopenia, neutropenia, anemia) caused by certain drugs (folic acid antagonists such as methotrexate, trimethoprim, pyrimethamine). Leucovorin may also be used to treat low folate levels in the brain caused by a rare genetic condition (cerebral folate transport deficiency).

Generic name: leucovorin calcium
Pronunciation: (lew-ko-VORE-in)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Leucovorin Calcium

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Indications

The following indications are listed for Leucovorin Calcium:

  • Bone Marrow Suppression Due To Folic Acid Antagonism
  • Methotrexate Toxicity
  • Pyrimethamine Toxicity
  • Sulfadiazine Toxicity
  • Trimethoprim Toxicity
  • Trimetrexate Toxicity

Also known as: Bone Marrow Depression Due To Folic Acid Antagonism, Bone Marrow Hypoplasia Due To Folic Acid Antagonism, Hypoplasia Of Bone Marrow Due To Folic Acid Antagonism, Mtx Toxicity, Myelosuppression Due To Folic Acid Antagonism, Tmp Toxicity.

Dosing

Dosage of leucovorin calcium is expressed in terms of leucovorin.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

There is no enhanced messaging for this drug.

Adverse reactions

There is no enhanced messaging for this drug.

Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data