Abnormal uterine bleeding

Abnormal uterine bleeding is a broad clinical condition characterized by bleeding from the uterine corpus that departs from normal parameters of frequency, regularity, duration, or volume in nonpregnant females of reproductive age It affects the female reproductive system and can present acutely as severe hemorrhage requiring emergent hemodynamic stabilization, or chronically over a prolonged duration

Abnormal uterine bleeding is a broad clinical condition characterized by bleeding from the uterine corpus that departs from normal parameters of frequency, regularity, duration, or volume in nonpregnant females of reproductive age

It affects the female reproductive system and can present acutely as severe hemorrhage requiring emergent hemodynamic stabilization, or chronically over a prolonged duration

Pathophysiologically, it is categorized by the FIGO PALM-COEIN classification into structural etiologies—such as uterine polyps, adenomyosis, leiomyomas, and malignancy—and nonstructural etiologies, including coagulopathies, ovulatory dysfunction, primary endometrial disorders, and iatrogenic causes

Pathophysiologically, it is categorized by the FIGO PALM-COEIN classification into structural etiologies—such as uterine polyps, adenomyosis, leiomyomas, and malignancy—and nonstructural etiologies, including coagulopathies, ovulatory dysfunction, primary endometrial disorders, and iatrogenic causes Clinically, these disruptions compromise local endometrial hemostasis or systemic endocrine signaling, frequently resulting in iron deficiency anemia and substantially diminished quality of life

Clinically, these disruptions compromise local endometrial hemostasis or systemic endocrine signaling, frequently resulting in iron deficiency anemia and substantially diminished quality of life