Indication
Allergic fungal rhinosinusitis
Allergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi. Read more about Allergic fungal rhinosinusitis
3 drugs 1 manufacturers
Drugs that treat it
Common Allergic fungal rhinosinusitis therapies.
DUPIXENT PEN (dupilumab)
DUPIXENT SYRINGE (dupilumab)
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Coming soonAllergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi.
It primarily affects the sinonasal tract of immunocompetent, typically atopic adolescents and young adults.
Pathophysiologically and clinically, it is characterized by extensive bilateral or unilateral nasal polyposis, immunoglobulin E-mediated hypersensitivity, and the accumulation of thick, eosinophil-rich "allergic mucin" containing noninvasive fungal hyphae and Charcot-Leyden crystals.
Continued accumulation of this dense mucin frequently produces an expansile mass effect that can erode adjacent bony sinus walls and extend toward the orbit or skull base.
- nih.gov
Allergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi It primarily affects the sinonasal tract of immunocompetent, typically atopic adolescents and young adults Pathophysiologically and clinically, it is characterized by extensive bilateral or unilateral nasal polyposis, immunoglobulin E-mediated hypersensitivity, and the accumulation of thick, ...
- nih.gov
Allergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi Pathophysiologically and clinically, it is characterized by extensive bilateral or unilateral nasal polyposis, immunoglobulin E-mediated hypersensitivity, and the accumulation of thick, eosinophil-rich "allergic mucin" containing noninvasive fungal hyphae and Charcot-Leyden crystals
- nih.gov
Allergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi Continued accumulation of this dense mucin frequently produces an expansile mass effect that can erode adjacent bony sinus walls and extend toward the orbit or skull base
- nih.gov
It primarily affects the sinonasal tract of immunocompetent, typically atopic adolescents and young adults
- mdpi.com
It primarily affects the sinonasal tract of immunocompetent, typically atopic adolescents and young adults
- nih.gov
Pathophysiologically and clinically, it is characterized by extensive bilateral or unilateral nasal polyposis, immunoglobulin E-mediated hypersensitivity, and the accumulation of thick, eosinophil-rich "allergic mucin" containing noninvasive fungal hyphae and Charcot-Leyden crystals Continued accumulation of this dense mucin frequently produces an expansile mass effect that can erode adjacent bony sinus walls and extend toward the orbit or skull base
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