Indication

Amenorrhea

Amenorrhea is a gynecologic condition characterized by the abnormal absence of menstruation in females of reproductive age. Read more about Amenorrhea

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About Amenorrhea.

Amenorrhea is a gynecologic condition characterized by the abnormal absence of menstruation in females of reproductive age.

It is broadly classified into primary amenorrhea, defined as the failure to reach menarche by age 15 or within three years of thelarche, and secondary amenorrhea, defined as the cessation of menses for three or more consecutive months in individuals with previously regular cycles or six months in those with irregular cycles.

Pathophysiologically, it arises from disruptions anywhere along the hypothalamic-pituitary-ovarian axis, systemic endocrine dysfunction, ovarian insufficiency, or anatomical abnormalities of the reproductive outflow tract.

Clinical manifestations typically stem from chronic anovulation and associated hypoestrogenism or hyperandrogenism, predisposing affected individuals to complications such as reduced bone mineral density, metabolic disturbances, and infertility.

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