Bronchiectasis

Bronchiectasis is a chronic pulmonary disorder of the respiratory system characterized by the permanent, abnormal dilation and structural destruction of the bronchial walls Pathophysiologically, it arises from a self-perpetuating cycle of impaired mucociliary clearance, chronic neutrophilic airway inflammation, persistent bacterial infection, and progressive tissue remodeling Defining clinical features include a chronic cough productive of copious, often purulent sputum, recurrent infectious exa...

Bronchiectasis is a chronic pulmonary disorder of the respiratory system characterized by the permanent, abnormal dilation and structural destruction of the bronchial walls Defining clinical features include a chronic cough productive of copious, often purulent sputum, recurrent infectious exacerbations, dyspnea, and progressive airflow obstruction

Pathophysiologically, it arises from a self-perpetuating cycle of impaired mucociliary clearance, chronic neutrophilic airway inflammation, persistent bacterial infection, and progressive tissue remodeling It can affect pediatric or adult populations and frequently develops secondary to conditions such as severe respiratory infections, cystic fibrosis, primary ciliary dyskinesia, or underlying immune deficiencies

It can affect pediatric or adult populations and frequently develops secondary to conditions such as severe respiratory infections, cystic fibrosis, primary ciliary dyskinesia, or underlying immune deficiencies

Defining clinical features include a chronic cough productive of copious, often purulent sputum, recurrent infectious exacerbations, dyspnea, and progressive airflow obstruction