Candidal meningitis

Candidal meningitis is an uncommon, life-threatening fungal infection characterized by inflammation of the leptomeninges surrounding the brain and spinal cord, caused by pathogenic *Candida* species The disease primarily affects premature or very-low-birth-weight neonates, patients undergoing neurosurgical interventions or harboring ventricular shunts, and severely immunocompromised hosts

Candidal meningitis is an uncommon, life-threatening fungal infection characterized by inflammation of the leptomeninges surrounding the brain and spinal cord, caused by pathogenic *Candida* species The disease primarily affects premature or very-low-birth-weight neonates, patients undergoing neurosurgical interventions or harboring ventricular shunts, and severely immunocompromised hosts Defining clinical features include fever, headache, altered mental status, and meningismus—or nonspecific se...

Candidal meningitis is an uncommon, life-threatening fungal infection characterized by inflammation of the leptomeninges surrounding the brain and spinal cord, caused by pathogenic *Candida* species

The disease primarily affects premature or very-low-birth-weight neonates, patients undergoing neurosurgical interventions or harboring ventricular shunts, and severely immunocompromised hosts Defining clinical features include fever, headache, altered mental status, and meningismus—or nonspecific sepsis-like decompensation in neonates—accompanied by cerebrospinal fluid abnormalities typically showing pleocytosis, elevated protein, hypoglycorrhachia, and positive fungal cultures

The disease primarily affects premature or very-low-birth-weight neonates, patients undergoing neurosurgical interventions or harboring ventricular shunts, and severely immunocompromised hosts

Pathophysiologically, it develops either via hematogenous seeding secondary to invasive candidemia or through direct inoculation during cranial surgery or device placement

Pathophysiologically, it develops either via hematogenous seeding secondary to invasive candidemia or through direct inoculation during cranial surgery or device placement

Defining clinical features include fever, headache, altered mental status, and meningismus—or nonspecific sepsis-like decompensation in neonates—accompanied by cerebrospinal fluid abnormalities typically showing pleocytosis, elevated protein, hypoglycorrhachia, and positive fungal cultures

Defining clinical features include fever, headache, altered mental status, and meningismus—or nonspecific sepsis-like decompensation in neonates—accompanied by cerebrospinal fluid abnormalities typically showing pleocytosis, elevated protein, hypoglycorrhachia, and positive fungal cultures