Chromoblastomycosis

Chromoblastomycosis is a chronic, progressive granulomatous fungal infection of the cutaneous and subcutaneous tissues caused by traumatic transcutaneous inoculation of pigmented dematiaceous fungi, most commonly *Fonsecaea pedrosoi* or *Cladophialophora carrionii* It predominantly affects outdoor and agricultural laborers in tropical and subtropical climates, typically manifesting on exposed areas such as the extremities

Chromoblastomycosis is a chronic, progressive granulomatous fungal infection of the cutaneous and subcutaneous tissues caused by traumatic transcutaneous inoculation of pigmented dematiaceous fungi, most commonly *Fonsecaea pedrosoi* or *Cladophialophora carrionii* Clinically, it begins as an indolent erythematous macule or papule that evolves over months to years into polymorphic verrucous plaques, nodular lesions, or cauliflower-like tumoral masses prone to ulceration, secondary bacterial infe...

Chromoblastomycosis is a chronic, progressive granulomatous fungal infection of the cutaneous and subcutaneous tissues caused by traumatic transcutaneous inoculation of pigmented dematiaceous fungi, most commonly *Fonsecaea pedrosoi* or *Cladophialophora carrionii*

It predominantly affects outdoor and agricultural laborers in tropical and subtropical climates, typically manifesting on exposed areas such as the extremities

Clinically, it begins as an indolent erythematous macule or papule that evolves over months to years into polymorphic verrucous plaques, nodular lesions, or cauliflower-like tumoral masses prone to ulceration, secondary bacterial infection, and scarring

Pathophysiologically, the disease is defined by suppurative granulomatous inflammation and microabscess formation, with histopathologic visualization of characteristic thick-walled, chestnut-brown muriform cells (sclerotic bodies) within tissue

Pathophysiologically, the disease is defined by suppurative granulomatous inflammation and microabscess formation, with histopathologic visualization of characteristic thick-walled, chestnut-brown muriform cells (sclerotic bodies) within tissue