HEPCLUDEX (bulevirtide acetate-gmod)
HEPATITIS D - NTCP INHIBITOR·CHRONIC HEPATITIS D
GILEAD SCIENCES
Indication
Chronic hepatitis D
Chronic hepatitis D is a persistent, progressive hepatic infection caused by the hepatitis D virus, a defective satellite RNA virus that obligately requires the presence of hepatitis B virus surface antigens for replication and propagation. Read more about Chronic hepatitis D
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Coming soonChronic hepatitis D is a persistent, progressive hepatic infection caused by the hepatitis D virus, a defective satellite RNA virus that obligately requires the presence of hepatitis B virus surface antigens for replication and propagation.
The disease exclusively affects individuals with concomitant hepatitis B virus infection, most frequently arising from a superinfection in chronic hepatitis B carriers.
Pathophysiologically, it is recognized as the most severe form of chronic viral hepatitis, characterized by ongoing viral replication (detectable hepatitis D virus RNA), elevated aminotransferases, necroinflammation, and rapid acceleration of hepatic fibrosis.
Compared to hepatitis B monoinfection, patients with chronic hepatitis D experience a substantially higher and faster risk of developing liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma.
- nih.gov
Chronic hepatitis D is a persistent, progressive hepatic infection caused by the hepatitis D virus, a defective satellite RNA virus that obligately requires the presence of hepatitis B virus surface antigens for replication and propagation Pathophysiologically, it is recognized as the most severe form of chronic viral hepatitis, characterized by ongoing viral replication (detectable hepatitis D virus RNA), elevated aminotransferases, necroinflammation, and rapid acceleration of hepatic fibrosis ...
- nih.gov
Chronic hepatitis D is a persistent, progressive hepatic infection caused by the hepatitis D virus, a defective satellite RNA virus that obligately requires the presence of hepatitis B virus surface antigens for replication and propagation The disease exclusively affects individuals with concomitant hepatitis B virus infection, most frequently arising from a superinfection in chronic hepatitis B carriers Pathophysiologically, it is recognized as the most severe form of chronic viral hepatitis, c...
- cdc.gov
The disease exclusively affects individuals with concomitant hepatitis B virus infection, most frequently arising from a superinfection in chronic hepatitis B carriers
- who.int
Pathophysiologically, it is recognized as the most severe form of chronic viral hepatitis, characterized by ongoing viral replication (detectable hepatitis D virus RNA), elevated aminotransferases, necroinflammation, and rapid acceleration of hepatic fibrosis Compared to hepatitis B monoinfection, patients with chronic hepatitis D experience a substantially higher and faster risk of developing liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma
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