Indication

Chronic kidney disease associated with type 2 diabetes mellitus

Chronic kidney disease associated with type 2 diabetes mellitus is a progressive microvascular complication affecting the renal system in individuals with type 2 diabetes. Read more about Chronic kidney disease associated with type 2 diabetes mellitus

4 drugs 4 manufacturers

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Drugs that treat it

Common Chronic kidney disease associated with type 2 diabetes mellitus therapies.

Showing 1–4 of 4 drugs

OZEMPIC (semaglutide)

INCRETIN MIMETIC/GLP-1 AND DUAL GIP/GLP-1 RECEPTOR AGONIST·TYPE 2 DIABETES MELLITUS·+2
NOVO NORDISK

INPEFA (sotagliflozin)

ANTIHYPERGLYCEMIC-SOD/GLUC COTRANSPORT-2 (SGLT2) INHIBITORS·CHRONIC HEART FAILURE·+2
LEXICON PHARMAC

OZEMPIC (semaglutide)

INCRETIN MIMETIC/GLP-1 AND DUAL GIP/GLP-1 RECEPTOR AGONIST·TYPE 2 DIABETES MELLITUS·+2
A-S MEDICATION
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About Chronic kidney disease associated with type 2 diabetes mellitus.

Chronic kidney disease associated with type 2 diabetes mellitus is a progressive microvascular complication affecting the renal system in individuals with type 2 diabetes.

It is clinically characterized by persistent albuminuria, an elevated urinary albumin-to-creatinine ratio, or a sustained decline in estimated glomerular filtration rate present for at least three months.

Pathophysiologically, sustained hyperglycemia, metabolic dysregulation, and intraglomerular hypertension induce oxidative stress, chronic inflammation, and renal fibrosis, leading to glomerular basement membrane thickening and mesangial expansion.

If unaddressed, this progressive renal damage significantly elevates the risk of cardiovascular events, cardiovascular death, and end-stage kidney disease.

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