Chronic rhinosinusitis without nasal polyps

Chronic rhinosinusitis without nasal polyps is a persistent inflammatory phenotype of the paranasal sinuses and nasal passages occurring in adults and children, distinguished by the clinical absence of polypoid tissue on endoscopy or cross-sectional imaging Pathophysiologically, the condition is typically driven by non-type 2 inflammatory pathways, marked by neutrophilic mucosal infiltration, goblet cell hyperplasia, basement membrane thickening, and tissue fibrosis

Chronic rhinosinusitis without nasal polyps is a persistent inflammatory phenotype of the paranasal sinuses and nasal passages occurring in adults and children, distinguished by the clinical absence of polypoid tissue on endoscopy or cross-sectional imaging It is defined by at least 12 consecutive weeks of cardinal upper respiratory symptoms, including nasal obstruction, anterior or posterior mucopurulent rhinorrhea, facial pain or pressure, and hyposmia

Chronic rhinosinusitis without nasal polyps is a persistent inflammatory phenotype of the paranasal sinuses and nasal passages occurring in adults and children, distinguished by the clinical absence of polypoid tissue on endoscopy or cross-sectional imaging

It is defined by at least 12 consecutive weeks of cardinal upper respiratory symptoms, including nasal obstruction, anterior or posterior mucopurulent rhinorrhea, facial pain or pressure, and hyposmia

It is defined by at least 12 consecutive weeks of cardinal upper respiratory symptoms, including nasal obstruction, anterior or posterior mucopurulent rhinorrhea, facial pain or pressure, and hyposmia