Indication

Complicated bacterial intra-abdominal infection

A complicated bacterial intra-abdominal infection refers to a severe infection of the gastrointestinal or hepatobiliary systems that extends beyond a primary hollow viscus or source organ into the normally sterile peritoneal cavity or retroperitoneal space. Read more about Complicated bacterial intra-abdominal infection

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About Complicated bacterial intra-abdominal infection.

A complicated bacterial intra-abdominal infection refers to a severe infection of the gastrointestinal or hepatobiliary systems that extends beyond a primary hollow viscus or source organ into the normally sterile peritoneal cavity or retroperitoneal space.

It typically manifests pathologically as localized abscess formation, localized peritonitis, or diffuse generalized peritonitis, frequently triggered by viscus perforation, transmural necrosis, trauma, or postoperative anastomotic disruption.

These infections are predominantly polymicrobial, driven by enteric Gram-negative bacilli, Gram-positive cocci, and anaerobic pathogens.

Clinically, affected patients present with acute abdominal pain, tenderness, systemic inflammatory signs, and hemodynamic instability, necessitating source control alongside targeted systemic antimicrobial therapy.

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