Disseminated sporotrichosis

Disseminated sporotrichosis is a rare, severe, systemic fungal infection caused by dimorphic fungi of the *Sporothrix* species complex (most notably *Sporothrix schenckii* and *Sporothrix brasiliensis*) It arises when the fungus spreads hematogenously beyond the initial cutaneous inoculation or pulmonary site, primarily affecting severely immunocompromised hosts, such as individuals with advanced HIV infection, hematologic malignancies, or immunosuppressive therapy

Disseminated sporotrichosis is a rare, severe, systemic fungal infection caused by dimorphic fungi of the *Sporothrix* species complex (most notably *Sporothrix schenckii* and *Sporothrix brasiliensis*) It arises when the fungus spreads hematogenously beyond the initial cutaneous inoculation or pulmonary site, primarily affecting severely immunocompromised hosts, such as individuals with advanced HIV infection, hematologic malignancies, or immunosuppressive therapy Clinically, the disease is cha...

It arises when the fungus spreads hematogenously beyond the initial cutaneous inoculation or pulmonary site, primarily affecting severely immunocompromised hosts, such as individuals with advanced HIV infection, hematologic malignancies, or immunosuppressive therapy Clinically, the disease is characterized by widespread, ulcerating cutaneous or subcutaneous lesions alongside multi-organ seeding, which commonly involves the osteoarticular system, lungs, eyes, and central nervous system, leading t...

It arises when the fungus spreads hematogenously beyond the initial cutaneous inoculation or pulmonary site, primarily affecting severely immunocompromised hosts, such as individuals with advanced HIV infection, hematologic malignancies, or immunosuppressive therapy

Clinically, the disease is characterized by widespread, ulcerating cutaneous or subcutaneous lesions alongside multi-organ seeding, which commonly involves the osteoarticular system, lungs, eyes, and central nervous system, leading to destructive tenosynovitis, osteomyelitis, or chronic fungal meningitis