Eczema

Eczema is a broad term encompassing chronic, relapsing inflammatory dermatoses of the integumentary system, most commonly referring to atopic dermatitis

Eczema is a broad term encompassing chronic, relapsing inflammatory dermatoses of the integumentary system, most commonly referring to atopic dermatitis It affects populations across all ages, presenting most frequently in early childhood and often persisting into or manifesting in adulthood Clinically, it is characterized by xerosis, intense pruritus, and localized erythematous macules or plaques that can progress to weeping, excoriation, and lichenification

Eczema is a broad term encompassing chronic, relapsing inflammatory dermatoses of the integumentary system, most commonly referring to atopic dermatitis It affects populations across all ages, presenting most frequently in early childhood and often persisting into or manifesting in adulthood Clinically, it is characterized by xerosis, intense pruritus, and localized erythematous macules or plaques that can progress to weeping, excoriation, and lichenification

Pathophysiologically, the condition is driven by epidermal barrier disruption, heightened transepidermal water loss, immune dysregulation predominantly mediated by type 2 cytokine signaling, and cutaneous neurosensory hyperactivity

Pathophysiologically, the condition is driven by epidermal barrier disruption, heightened transepidermal water loss, immune dysregulation predominantly mediated by type 2 cytokine signaling, and cutaneous neurosensory hyperactivity

Clinically, it is characterized by xerosis, intense pruritus, and localized erythematous macules or plaques that can progress to weeping, excoriation, and lichenification