Episodic cluster headache

Episodic cluster headache is a primary neurovascular headache disorder classified under the trigeminal autonomic cephalalgias, primarily affecting adults and demonstrating a notable male predominance

Episodic cluster headache is a primary neurovascular headache disorder classified under the trigeminal autonomic cephalalgias, primarily affecting adults and demonstrating a notable male predominance

Episodic cluster headache is a primary neurovascular headache disorder classified under the trigeminal autonomic cephalalgias, primarily affecting adults and demonstrating a notable male predominance During active bouts, patients experience excruciating, strictly unilateral pain localized to the orbital, supraorbital, or temporal regions that lasts 15 to 180 minutes and recurs up to eight times daily, often exhibiting strict circadian and circannual periodicity Pathophysiologically driven by hyp...

It is characterized by recurring cluster periods, or bouts, typically lasting from seven days to one year, separated by pain-free remission intervals lasting at least three months

It is characterized by recurring cluster periods, or bouts, typically lasting from seven days to one year, separated by pain-free remission intervals lasting at least three months Pathophysiologically driven by hypothalamic dysregulation and trigeminovascular system activation, attacks are accompanied by ipsilateral cranial autonomic symptoms—such as lacrimation, conjunctival injection, nasal congestion, and ptosis—as well as pronounced physical restlessness

During active bouts, patients experience excruciating, strictly unilateral pain localized to the orbital, supraorbital, or temporal regions that lasts 15 to 180 minutes and recurs up to eight times daily, often exhibiting strict circadian and circannual periodicity

During active bouts, patients experience excruciating, strictly unilateral pain localized to the orbital, supraorbital, or temporal regions that lasts 15 to 180 minutes and recurs up to eight times daily, often exhibiting strict circadian and circannual periodicity

Pathophysiologically driven by hypothalamic dysregulation and trigeminovascular system activation, attacks are accompanied by ipsilateral cranial autonomic symptoms—such as lacrimation, conjunctival injection, nasal congestion, and ptosis—as well as pronounced physical restlessness