Indication

Extensive-stage small cell lung cancer

Extensive-stage small cell lung cancer is an advanced, highly aggressive malignancy of neuroendocrine origin affecting the respiratory system, strongly associated with tobacco exposure. Read more about Extensive-stage small cell lung cancer

2 drugs 2 manufacturers

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Drugs that treat it

Common Extensive-stage small cell lung cancer therapies.

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IMFINZI (durvalumab)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY·BILIARY TRACT MALIGNANCY·+10
AstraZeneca Pharmaceuticals
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About Extensive-stage small cell lung cancer.

Extensive-stage small cell lung cancer is an advanced, highly aggressive malignancy of neuroendocrine origin affecting the respiratory system, strongly associated with tobacco exposure.

It is clinically defined as cancer that has spread beyond a single hemithorax and ipsilateral regional lymph nodes—or cannot be encompassed within a tolerable single radiation field—commonly involving contralateral thoracic structures, malignant pleural or pericardial effusions, or distant hematogenous metastases to organs such as the liver, brain, bone, and adrenal glands.

Pathophysiologically characterized by rapid cellular proliferation, genomic instability, and widespread early dissemination, it accounts for approximately two-thirds of initial small cell lung cancer diagnoses and carries a poor long-term prognosis.

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