Indication

Full-thickness articular cartilage defect of the knee

A full-thickness articular cartilage defect of the knee is a severe musculoskeletal condition characterized by localized loss of the hyaline cartilage covering the distal femur, proximal tibia, or patella, extending through the entire cartilage depth to expose the underlying subchondral bone. Read more about Full-thickness articular cartilage defect of the knee

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About Full-thickness articular cartilage defect of the knee.

A full-thickness articular cartilage defect of the knee is a severe musculoskeletal condition characterized by localized loss of the hyaline cartilage covering the distal femur, proximal tibia, or patella, extending through the entire cartilage depth to expose the underlying subchondral bone.

Most commonly affecting active adolescents and adults following acute trauma, repetitive microtrauma, or osteochondritis dissecans, these lesions typically correspond to high-grade chondral damage such as Outerbridge Grade IV or International Cartilage Repair Society Grade 3 to 4.

Because mature articular cartilage is avascular and aneural, it lacks the innate regenerative capacity to self-repair, resulting in persistent localized joint pain, recurrent effusions, mechanical catching, functional impairment, and an elevated risk of secondary osteoarthritis.

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