Heart Failure with Preserved Ejection Fraction

Heart failure with preserved ejection fraction is a clinical cardiovascular syndrome characterized by typical symptoms and signs of heart failure—such as dyspnea, fatigue, and peripheral edema—occurring alongside a normal or near-normal left ventricular ejection fraction, typically defined as 50% or greater

Heart failure with preserved ejection fraction is a clinical cardiovascular syndrome characterized by typical symptoms and signs of heart failure—such as dyspnea, fatigue, and peripheral edema—occurring alongside a normal or near-normal left ventricular ejection fraction, typically defined as 50% or greater This structural and diastolic dysfunction leads to elevated left ventricular filling pressures at rest or during exertion, culminating in systemic and pulmonary venous congestion despite pres...

Affecting primarily older adults, women, and individuals with comorbid cardiometabolic disorders such as hypertension, diabetes, and obesity, it stems from impaired ventricular relaxation and increased myocardial stiffness

Affecting primarily older adults, women, and individuals with comorbid cardiometabolic disorders such as hypertension, diabetes, and obesity, it stems from impaired ventricular relaxation and increased myocardial stiffness

This structural and diastolic dysfunction leads to elevated left ventricular filling pressures at rest or during exertion, culminating in systemic and pulmonary venous congestion despite preserved systolic pump capacity