NOVOSEVEN RT (coagulation factor VIIa (recombinant))
FACTOR VII·BLEEDING EPISODE IN HEMOPHILIA A·+6
NOVO NORDISK
Indication
Hereditary factor VII deficiency disease
Hereditary factor VII deficiency disease is a rare, inherited bleeding disorder transmitted in an autosomal recessive pattern due to pathogenic variants in the *F7* gene. Read more about Hereditary factor VII deficiency disease
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Coming soonHereditary factor VII deficiency disease is a rare, inherited bleeding disorder transmitted in an autosomal recessive pattern due to pathogenic variants in the *F7* gene.
The condition impairs the extrinsic coagulation pathway because of deficient or dysfunctional coagulation factor VII, an essential vitamin K–dependent plasma protease.
It affects both males and females across all age groups, with clinical manifestations ranging widely from asymptomatic states to severe hemorrhages that do not always correlate with circulating factor VII levels.
Defining clinical features include mucocutaneous bleeding—such as recurrent epistaxis, gingival bleeding, menorrhagia, and hematomas—as well as potentially fatal central nervous system or gastrointestinal hemorrhages, accompanied by an isolated prolongation of the prothrombin time.
- nih.gov
Hereditary factor VII deficiency disease is a rare, inherited bleeding disorder transmitted in an autosomal recessive pattern due to pathogenic variants in the *F7* gene
- medlineplus.gov
Hereditary factor VII deficiency disease is a rare, inherited bleeding disorder transmitted in an autosomal recessive pattern due to pathogenic variants in the *F7* gene The condition impairs the extrinsic coagulation pathway because of deficient or dysfunctional coagulation factor VII, an essential vitamin K–dependent plasma protease Defining clinical features include mucocutaneous bleeding—such as recurrent epistaxis, gingival bleeding, menorrhagia, and hematomas—as well as potentially fatal c...
- medlineplus.gov
The condition impairs the extrinsic coagulation pathway because of deficient or dysfunctional coagulation factor VII, an essential vitamin K–dependent plasma protease
- nih.gov
It affects both males and females across all age groups, with clinical manifestations ranging widely from asymptomatic states to severe hemorrhages that do not always correlate with circulating factor VII levels
- medlineplus.gov
Defining clinical features include mucocutaneous bleeding—such as recurrent epistaxis, gingival bleeding, menorrhagia, and hematomas—as well as potentially fatal central nervous system or gastrointestinal hemorrhages, accompanied by an isolated prolongation of the prothrombin time
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