Hyperhidrosis

Hyperhidrosis is an autonomic nervous system and dermatologic disorder characterized by excessive sweat production beyond what is physiologically required for thermal regulation or environmental adaptation

It primarily affects the eccrine sweat glands and can manifest either as primary (idiopathic) focal hyperhidrosis—most frequently involving the axillae, palms, soles, and craniofacial regions—or as secondary generalized hyperhidrosis arising from underlying endocrine, neurologic, infectious, or neoplastic etiologies, as well as adverse drug reactions Pathophysiologically, the condition involves neurogenic hyperactivity of central and peripheral sympathetic cholinergic pathways innervating histol...

It primarily affects the eccrine sweat glands and can manifest either as primary (idiopathic) focal hyperhidrosis—most frequently involving the axillae, palms, soles, and craniofacial regions—or as secondary generalized hyperhidrosis arising from underlying endocrine, neurologic, infectious, or neoplastic etiologies, as well as adverse drug reactions

Pathophysiologically, the condition involves neurogenic hyperactivity of central and peripheral sympathetic cholinergic pathways innervating histologically normal eccrine glands, producing substantial physical discomfort, epidermal maceration, and psychosocial impairment

Pathophysiologically, the condition involves neurogenic hyperactivity of central and peripheral sympathetic cholinergic pathways innervating histologically normal eccrine glands, producing substantial physical discomfort, epidermal maceration, and psychosocial impairment