Indication

Japanese encephalitis vaccination

Japanese encephalitis vaccination is an active immunization procedure indicated for the prevention of disease caused by the mosquito-borne Japanese encephalitis virus, a neurotropic flavivirus endemic across parts of Asia and the Western Pacific. Read more about Japanese encephalitis vaccination

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About Japanese encephalitis vaccination.

Japanese encephalitis vaccination is an active immunization procedure indicated for the prevention of disease caused by the mosquito-borne Japanese encephalitis virus, a neurotropic flavivirus endemic across parts of Asia and the Western Pacific.

The primary target population includes at-risk individuals, such as travelers spending extended periods in endemic or rural areas, persons with outdoor or occupational exposure, and laboratory personnel working with the virus.

Infection primarily targets the central nervous system, where neuroinvasion and intense neuroinflammation can progress from non-specific febrile symptoms to acute encephalopathy, seizures, focal neurological deficits, and coma.

Clinically apparent encephalitis carries high mortality rates and causes permanent neurocognitive or motor sequelae in a large proportion of survivors, underscoring the role of pre-exposure prophylaxis.

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