Indication
Lower limb spasticity
Lower limb spasticity is a neuromuscular condition characterized by a velocity-dependent increase in tonic stretch reflexes and muscle tone affecting the hip, thigh, leg, ankle, or foot. Read more about Lower limb spasticity
6 drugs 5 manufacturers
Drugs that treat it
Common Lower limb spasticity therapies.
DYSPORT (abobotulinumtoxinA)
BOTOX COSMETIC (onabotulinumtoxinA)
DYSPORT (abobotulinumtoxinA)
BOTOX (onabotulinumtoxinA)
DYSPORT (abobotulinumtoxinA)
News & literature
Coming soonRelated codes
Coming soonRelated conditions & guidelines
Coming soonLower limb spasticity is a neuromuscular condition characterized by a velocity-dependent increase in tonic stretch reflexes and muscle tone affecting the hip, thigh, leg, ankle, or foot.
It develops as a component of upper motor neuron syndrome following central nervous system injury—such as from stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, or cerebral palsy—which disrupts descending inhibitory supraspinal control and produces hyperexcitable spinal stretch reflex arcs.
Clinically, affected individuals present with exaggerated tendon jerks, clonus, painful spasms, and abnormal lower-extremity posture, commonly involving excessive knee extension, hip adduction, or ankle plantarflexion (equinovarus deformity).
Without adequate intervention, this hypertonia can significantly impair mobility, gait, and transfers, often predisposing patients to secondary soft-tissue contractures and musculoskeletal deformities.
- nih.gov
Lower limb spasticity is a neuromuscular condition characterized by a velocity-dependent increase in tonic stretch reflexes and muscle tone affecting the hip, thigh, leg, ankle, or foot Clinically, affected individuals present with exaggerated tendon jerks, clonus, painful spasms, and abnormal lower-extremity posture, commonly involving excessive knee extension, hip adduction, or ankle plantarflexion (equinovarus deformity)
- nih.gov
Lower limb spasticity is a neuromuscular condition characterized by a velocity-dependent increase in tonic stretch reflexes and muscle tone affecting the hip, thigh, leg, ankle, or foot
- nih.gov
It develops as a component of upper motor neuron syndrome following central nervous system injury—such as from stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, or cerebral palsy—which disrupts descending inhibitory supraspinal control and produces hyperexcitable spinal stretch reflex arcs Clinically, affected individuals present with exaggerated tendon jerks, clonus, painful spasms, and abnormal lower-extremity posture, commonly involving excessive knee extension, hip addu...
- medlink.com
Clinically, affected individuals present with exaggerated tendon jerks, clonus, painful spasms, and abnormal lower-extremity posture, commonly involving excessive knee extension, hip adduction, or ankle plantarflexion (equinovarus deformity)
- nih.gov
Without adequate intervention, this hypertonia can significantly impair mobility, gait, and transfers, often predisposing patients to secondary soft-tissue contractures and musculoskeletal deformities
- physio-pedia.com
Without adequate intervention, this hypertonia can significantly impair mobility, gait, and transfers, often predisposing patients to secondary soft-tissue contractures and musculoskeletal deformities
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