Lymphomatous meningitis

Lymphomatous meningitis is a severe neuro-oncologic manifestation characterized by the dissemination and infiltration of malignant lymphoid cells into the leptomeninges and cerebrospinal fluid compartments of the central nervous system Pathophysiologically, the tumor cells seed the subarachnoid space, disrupting cerebrospinal fluid dynamics and prompting multifocal inflammation across the entire neuraxis

Lymphomatous meningitis is a severe neuro-oncologic manifestation characterized by the dissemination and infiltration of malignant lymphoid cells into the leptomeninges and cerebrospinal fluid compartments of the central nervous system It primarily occurs as a secondary metastatic complication of aggressive systemic non-Hodgkin lymphomas, though it can also arise in the setting of primary central nervous system lymphoma Pathophysiologically, the tumor cells seed the subarachnoid space, disruptin...

It primarily occurs as a secondary metastatic complication of aggressive systemic non-Hodgkin lymphomas, though it can also arise in the setting of primary central nervous system lymphoma

This diffuse involvement leads to varied neurological deficits, typically presenting with combinations of cranial neuropathies, radicular pain or motor weakness, altered mental status, and symptoms of elevated intracranial pressure such as persistent headache, nausea, and vomiting

This diffuse involvement leads to varied neurological deficits, typically presenting with combinations of cranial neuropathies, radicular pain or motor weakness, altered mental status, and symptoms of elevated intracranial pressure such as persistent headache, nausea, and vomiting