Macular edema associated with non-infectious uveitis

Macular edema associated with non-infectious uveitis is a sight-threatening ocular complication characterized by intraretinal and subretinal fluid accumulation within the macula, the central portion of the retina responsible for high-acuity vision It occurs secondary to non-infectious, immune-mediated intraocular inflammation that can affect the anterior, intermediate, posterior, or panuveal tracts of the eye Pathophysiologically, sustained inflammatory cytokine release disrupts both the inner a...

Macular edema associated with non-infectious uveitis is a sight-threatening ocular complication characterized by intraretinal and subretinal fluid accumulation within the macula, the central portion of the retina responsible for high-acuity vision

Macular edema associated with non-infectious uveitis is a sight-threatening ocular complication characterized by intraretinal and subretinal fluid accumulation within the macula, the central portion of the retina responsible for high-acuity vision Pathophysiologically, sustained inflammatory cytokine release disrupts both the inner and outer blood-retinal barriers, increasing microvascular permeability and overwhelming normal fluid-clearance mechanisms

It occurs secondary to non-infectious, immune-mediated intraocular inflammation that can affect the anterior, intermediate, posterior, or panuveal tracts of the eye

Pathophysiologically, sustained inflammatory cytokine release disrupts both the inner and outer blood-retinal barriers, increasing microvascular permeability and overwhelming normal fluid-clearance mechanisms

Clinically, this results in retinal thickening, cystoid macular changes, blurred central vision, and metamorphopsia, making it a leading cause of permanent visual impairment in patients with chronic ocular inflammatory disease