Neurotrophic keratitis

Neurotrophic keratitis is a rare, degenerative ocular disease of the cornea resulting from impaired sensory innervation along the trigeminal nerve Patients frequently experience an insidious progression with minimal discomfort despite severe corneal damage, predisposing them to secondary infection, scarring, and irreversible vision loss

Neurotrophic keratitis is a rare, degenerative ocular disease of the cornea resulting from impaired sensory innervation along the trigeminal nerve Loss of corneal sensitivity diminishes essential trophic support, tear production, and the protective blink reflex, which impairs ocular surface maintenance and epithelial wound healing Clinically, it presents along a continuum ranging from punctate epithelial keratopathy to persistent epithelial defects and, in advanced stages, sterile stromal ulcera...

Loss of corneal sensitivity diminishes essential trophic support, tear production, and the protective blink reflex, which impairs ocular surface maintenance and epithelial wound healing Clinically, it presents along a continuum ranging from punctate epithelial keratopathy to persistent epithelial defects and, in advanced stages, sterile stromal ulceration, melting, and corneal perforation