Indication
Nonalcoholic steatohepatitis
Nonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption. Read more about Nonalcoholic steatohepatitis
3 drugs 2 manufacturers
Drugs that treat it
Common Nonalcoholic steatohepatitis therapies.
WEGOVY (semaglutide)
WEGOVY HD (semaglutide)
News & literature
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Coming soonRelated conditions & guidelines
Coming soonNonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption.
It is histopathologically defined by hepatic steatosis accompanied by lobular inflammation and hepatocyte injury, notably ballooning degeneration, with or without associated fibrosis.
Pathophysiologically driven by lipotoxicity, oxidative stress, and immune-mediated inflammatory cascades, this condition carries a substantial risk of progressing to advanced fibrosis, cirrhosis, end-stage liver failure, and hepatocellular carcinoma.
- nih.gov
Nonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption Pathophysiologically driven by lipotoxicity, oxidative stress, and immune-mediated inflammatory cascades, this condition carries a substantial risk of progressing to advanced fibrosis, cirrhosis, end-stage l...
- nih.gov
Nonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption It is histopathologically defined by hepatic steatosis accompanied by lobular inflammation and hepatocyte injury, notably ballooning degeneration, with or without associated fibrosis Pathophysiologically dri...
- nih.gov
Nonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption
- nih.gov
It is histopathologically defined by hepatic steatosis accompanied by lobular inflammation and hepatocyte injury, notably ballooning degeneration, with or without associated fibrosis
- nih.gov
Pathophysiologically driven by lipotoxicity, oxidative stress, and immune-mediated inflammatory cascades, this condition carries a substantial risk of progressing to advanced fibrosis, cirrhosis, end-stage liver failure, and hepatocellular carcinoma
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