Indication

Nonexudative age-related macular degeneration

Nonexudative age-related macular degeneration, commonly termed dry or non-neovascular age-related macular degeneration, is a chronic, progressive neurodegenerative disorder of the central retina that predominantly affects older adults. Read more about Nonexudative age-related macular degeneration

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Drugs that treat it

Common Nonexudative age-related macular degeneration therapies.

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SYFOVRE (pegcetacoplan/PF)

OPHTHALMIC - MACULAR DEGENERATION AGENTS·NONEXUDATIVE AGE-RELATED MACULAR DEGENERATION
Apellis Pharmaceuticals
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About Nonexudative age-related macular degeneration.

Nonexudative age-related macular degeneration, commonly termed dry or non-neovascular age-related macular degeneration, is a chronic, progressive neurodegenerative disorder of the central retina that predominantly affects older adults.

It is pathologically characterized by the accumulation of extracellular lipid- and protein-rich deposits, known as drusen, between the retinal pigment epithelium and Bruch membrane.

This process leads to progressive retinal pigment epithelium dysfunction, photoreceptor loss, and pigmentary abnormalities within the macula in the absence of exudation, choroidal neovascularization, or subretinal fluid leakage.

In its advanced stages, it manifests as geographic atrophy, resulting in gradual, irreversible impairment of fine, high-acuity central vision.

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