Indication

Paraganglioma

Paraganglioma is a rare neuroendocrine neoplasm that arises from neural crest–derived extra-adrenal chromaffin or non-chromaffin cells within autonomic paraganglia. Read more about Paraganglioma

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AZEDRA DOSIMETRIC (iobenguane iodine-131)

PHEOCHROMOCYTOMA·+1

PROGENICS PHARM

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About Paraganglioma.

Paraganglioma is a rare neuroendocrine neoplasm that arises from neural crest–derived extra-adrenal chromaffin or non-chromaffin cells within autonomic paraganglia.

Affecting the sympathetic or parasympathetic nervous systems, these tumors can develop along peripheral nerve and vascular pathways throughout the head, neck, thorax, abdomen, and pelvis.

Parasympathetic paragangliomas, predominantly found in the head and neck, are typically non-secretory and present as slow-growing, locally compressive masses.

Conversely, sympathetic paragangliomas generally arise in the retroperitoneum or pelvis and frequently hypersecrete catecholamines, producing classic manifestations such as episodic hypertension, palpitations, headaches, and diaphoresis.

Although often benign, all paragangliomas possess variable metastatic potential and exhibit a strong association with hereditary cancer susceptibility syndromes, notably involving germline mutations in succinate dehydrogenase subunit genes.

cancer.gov
Paraganglioma is a rare neuroendocrine neoplasm that arises from neural crest–derived extra-adrenal chromaffin or non-chromaffin cells within autonomic paraganglia Affecting the sympathetic or parasympathetic nervous systems, these tumors can develop along peripheral nerve and vascular pathways throughout the head, neck, thorax, abdomen, and pelvis Conversely, sympathetic paragangliomas generally arise in the retroperitoneum or pelvis and frequently hypersecrete catecholamines, producing classic...
cancer.gov
Paraganglioma is a rare neuroendocrine neoplasm that arises from neural crest–derived extra-adrenal chromaffin or non-chromaffin cells within autonomic paraganglia
nih.gov
Paraganglioma is a rare neuroendocrine neoplasm that arises from neural crest–derived extra-adrenal chromaffin or non-chromaffin cells within autonomic paraganglia Conversely, sympathetic paragangliomas generally arise in the retroperitoneum or pelvis and frequently hypersecrete catecholamines, producing classic manifestations such as episodic hypertension, palpitations, headaches, and diaphoresis
nih.gov
Paraganglioma is a rare neuroendocrine neoplasm that arises from neural crest–derived extra-adrenal chromaffin or non-chromaffin cells within autonomic paraganglia Affecting the sympathetic or parasympathetic nervous systems, these tumors can develop along peripheral nerve and vascular pathways throughout the head, neck, thorax, abdomen, and pelvis Parasympathetic paragangliomas, predominantly found in the head and neck, are typically non-secretory and present as slow-growing, locally compressiv...
cancer.gov
Affecting the sympathetic or parasympathetic nervous systems, these tumors can develop along peripheral nerve and vascular pathways throughout the head, neck, thorax, abdomen, and pelvis
cancer.gov
Parasympathetic paragangliomas, predominantly found in the head and neck, are typically non-secretory and present as slow-growing, locally compressive masses Although often benign, all paragangliomas possess variable metastatic potential and exhibit a strong association with hereditary cancer susceptibility syndromes, notably involving germline mutations in succinate dehydrogenase subunit genes
nih.gov
Parasympathetic paragangliomas, predominantly found in the head and neck, are typically non-secretory and present as slow-growing, locally compressive masses Although often benign, all paragangliomas possess variable metastatic potential and exhibit a strong association with hereditary cancer susceptibility syndromes, notably involving germline mutations in succinate dehydrogenase subunit genes
nih.gov
Conversely, sympathetic paragangliomas generally arise in the retroperitoneum or pelvis and frequently hypersecrete catecholamines, producing classic manifestations such as episodic hypertension, palpitations, headaches, and diaphoresis Although often benign, all paragangliomas possess variable metastatic potential and exhibit a strong association with hereditary cancer susceptibility syndromes, notably involving germline mutations in succinate dehydrogenase subunit genes

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