Peptostreptococcus joint infection

*Peptostreptococcus* joint infection is a localized septic arthritis or periprosthetic joint infection of the musculoskeletal system caused by anaerobic, Gram-positive cocci belonging to the genus *Peptostreptococcus* or related anaerobic Gram-positive coccal taxa It primarily develops in individuals with prosthetic joint implants, prior orthopedic surgeries, underlying chronic arthropathies, trauma, or systemic immunocompromise

It primarily develops in individuals with prosthetic joint implants, prior orthopedic surgeries, underlying chronic arthropathies, trauma, or systemic immunocompromise

Pathophysiologically, the organism colonizes synovial tissue or implant surfaces—frequently as part of an indolent or polymicrobial biofilm—triggering acute or chronic suppurative inflammation Affected patients typically present with progressive localized joint pain, periarticular swelling, erythema, reduced range of motion, and inflammatory or purulent synovial fluid accumulations

Pathophysiologically, the organism colonizes synovial tissue or implant surfaces—frequently as part of an indolent or polymicrobial biofilm—triggering acute or chronic suppurative inflammation

Affected patients typically present with progressive localized joint pain, periarticular swelling, erythema, reduced range of motion, and inflammatory or purulent synovial fluid accumulations