Pneumonia due to Klebsiella pneumoniae

Pneumonia due to *Klebsiella pneumoniae* is an acute lower respiratory tract infection characterized by severe inflammation and exudative consolidation of the pulmonary parenchyma It most commonly manifests as a healthcare-associated or ventilator-associated pneumonia in hospitalized or immunocompromised individuals, but it can also cause aggressive community-acquired infections, particularly in populations with diabetes mellitus, chronic lung disease, or alcohol use disorder Pathophysiologicall...

Pneumonia due to *Klebsiella pneumoniae* is an acute lower respiratory tract infection characterized by severe inflammation and exudative consolidation of the pulmonary parenchyma This frequently results in alveolar destruction, lung abscesses, cavitation, and the characteristic production of thick, blood-tinged "currant jelly" sputum

It most commonly manifests as a healthcare-associated or ventilator-associated pneumonia in hospitalized or immunocompromised individuals, but it can also cause aggressive community-acquired infections, particularly in populations with diabetes mellitus, chronic lung disease, or alcohol use disorder

Pathophysiologically, the organism—an encapsulated, gram-negative bacillus—uses robust polysaccharide capsules and endotoxins to evade phagocytosis and induce intense tissue necrosis

This frequently results in alveolar destruction, lung abscesses, cavitation, and the characteristic production of thick, blood-tinged "currant jelly" sputum