Primary focal hyperhidrosis of axilla

Primary focal hyperhidrosis of the axilla is a chronic neurodermatologic disorder characterized by excessive, bilateral, and relatively symmetric sweat production in the underarm regions that substantially exceeds physiological requirements for thermoregulation

Primary focal hyperhidrosis of the axilla is a chronic neurodermatologic disorder characterized by excessive, bilateral, and relatively symmetric sweat production in the underarm regions that substantially exceeds physiological requirements for thermoregulation Affecting children, adolescents, and adults with typical onset before age 25, the condition stems from autonomic dysregulation marked by hyperactive sympathetic cholinergic signaling to histologically normal eccrine glands rather than an ...

Primary focal hyperhidrosis of the axilla is a chronic neurodermatologic disorder characterized by excessive, bilateral, and relatively symmetric sweat production in the underarm regions that substantially exceeds physiological requirements for thermoregulation Affecting children, adolescents, and adults with typical onset before age 25, the condition stems from autonomic dysregulation marked by hyperactive sympathetic cholinergic signaling to histologically normal eccrine glands rather than an ...

Clinical manifestations include visible, unprovoked underarm sweating occurring at least weekly during waking hours, often exacerbated by emotional stress or heat, which leads to physical skin maceration, clothing disruption, and substantial psychosocial impairment