Pseudobulbar affect

Pseudobulbar affect is a neurological disorder of emotional expression characterized by sudden, involuntary, and uncontrollable episodes of laughing or crying These outbursts are exaggerated or completely incongruent with the individual's actual internal mood or the external social context

Pseudobulbar affect is a neurological disorder of emotional expression characterized by sudden, involuntary, and uncontrollable episodes of laughing or crying These outbursts are exaggerated or completely incongruent with the individual's actual internal mood or the external social context Pathophysiologically, it is attributed to the disruption of frontocerebellar neural networks and cortico-ponto-cerebellar circuits responsible for the modulation and voluntary control of motor emotional expres...

The condition arises secondary to underlying central nervous system dysfunction or injury, commonly occurring in populations with amyotrophic lateral sclerosis, multiple sclerosis, stroke, traumatic brain injury, Alzheimer disease, or Parkinson disease

The condition arises secondary to underlying central nervous system dysfunction or injury, commonly occurring in populations with amyotrophic lateral sclerosis, multiple sclerosis, stroke, traumatic brain injury, Alzheimer disease, or Parkinson disease

Pathophysiologically, it is attributed to the disruption of frontocerebellar neural networks and cortico-ponto-cerebellar circuits responsible for the modulation and voluntary control of motor emotional expression