Indication

Pulmonary cryptococcosis

Pulmonary cryptococcosis is an invasive fungal infection of the respiratory tract caused by the inhalation of environmental basidiospores or desiccated yeast cells, most commonly from the *Cryptococcus neoformans* or *Cryptococcus gattii* species complexes. Read more about Pulmonary cryptococcosis

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About Pulmonary cryptococcosis.

Pulmonary cryptococcosis is an invasive fungal infection of the respiratory tract caused by the inhalation of environmental basidiospores or desiccated yeast cells, most commonly from the *Cryptococcus neoformans* or *Cryptococcus gattii* species complexes.

While it primarily affects immunocompromised individuals—notably those with advanced HIV disease, solid organ transplants, or prolonged immunosuppressive therapy—it can also develop in immunocompetent hosts.

The clinical spectrum ranges from asymptomatic localized colonization to subacute or acute pneumonia, with symptoms including cough, dyspnea, pleuritic chest pain, and fever.

Pathophysiologically characterized by granulomatous or tissue-invasive inflammation, the infection typically manifests radiographically as solitary or multiple pulmonary nodules, cryptococcomas, consolidations, or cavitary lesions, carrying a significant risk of hematogenous dissemination to the central nervous system.

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