ARCALYST (rilonacept)
MUCKLE-WELLS SYNDROME·+3
Regeneron Pharmaceuticals, Inc.
Indication
Recurrent pericarditis
Recurrent pericarditis is an autoinflammatory cardiovascular condition characterized by repeated flares of inflammation affecting the fibroelastic sac surrounding the heart, occurring after a documented symptom-free interval of at least 4 to 6 weeks following an initial or prior acute episode. Read more about Recurrent pericarditis
2 drugs 2 manufacturers
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Common Recurrent pericarditis therapies.
ARCALYST (rilonacept)
ANTI-INFLAMMATORY - INTERLEUKIN 1 RECEPTOR ANTAGONIST·MUCKLE-WELLS SYNDROME·+3
KINIKSA PHARMAC
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Coming soonRelated codes
Coming soonRelated conditions & guidelines
Coming soonRecurrent pericarditis is an autoinflammatory cardiovascular condition characterized by repeated flares of inflammation affecting the fibroelastic sac surrounding the heart, occurring after a documented symptom-free interval of at least 4 to 6 weeks following an initial or prior acute episode.
It develops as a complication in approximately 15% to 30% of patients following acute pericarditis and is predominantly driven by innate immune dysregulation, often involving the interleukin-1 signaling cascade.
Defining clinical features include positional, pleuritic chest pain alongside objective evidence of disease activity, such as elevated systemic inflammatory biomarkers, a pericardial friction rub, diagnostic electrocardiographic changes, new or worsening pericardial effusion, and late gadolinium enhancement on cardiac magnetic resonance imaging.
- heart.org
Recurrent pericarditis is an autoinflammatory cardiovascular condition characterized by repeated flares of inflammation affecting the fibroelastic sac surrounding the heart, occurring after a documented symptom-free interval of at least 4 to 6 weeks following an initial or prior acute episode
- nih.gov
Recurrent pericarditis is an autoinflammatory cardiovascular condition characterized by repeated flares of inflammation affecting the fibroelastic sac surrounding the heart, occurring after a documented symptom-free interval of at least 4 to 6 weeks following an initial or prior acute episode It develops as a complication in approximately 15% to 30% of patients following acute pericarditis and is predominantly driven by innate immune dysregulation, often involving the interleukin-1 signaling cas...
- rarediseases.org
Recurrent pericarditis is an autoinflammatory cardiovascular condition characterized by repeated flares of inflammation affecting the fibroelastic sac surrounding the heart, occurring after a documented symptom-free interval of at least 4 to 6 weeks following an initial or prior acute episode
- nih.gov
It develops as a complication in approximately 15% to 30% of patients following acute pericarditis and is predominantly driven by innate immune dysregulation, often involving the interleukin-1 signaling cascade
- nih.gov
Defining clinical features include positional, pleuritic chest pain alongside objective evidence of disease activity, such as elevated systemic inflammatory biomarkers, a pericardial friction rub, diagnostic electrocardiographic changes, new or worsening pericardial effusion, and late gadolinium enhancement on cardiac magnetic resonance imaging
- acc.org
Defining clinical features include positional, pleuritic chest pain alongside objective evidence of disease activity, such as elevated systemic inflammatory biomarkers, a pericardial friction rub, diagnostic electrocardiographic changes, new or worsening pericardial effusion, and late gadolinium enhancement on cardiac magnetic resonance imaging
- acc.org
Defining clinical features include positional, pleuritic chest pain alongside objective evidence of disease activity, such as elevated systemic inflammatory biomarkers, a pericardial friction rub, diagnostic electrocardiographic changes, new or worsening pericardial effusion, and late gadolinium enhancement on cardiac magnetic resonance imaging
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