Indication

Rhinocerebral phycomycosis

Rhinocerebral phycomycosis—more commonly termed rhinocerebral mucormycosis or zygomycosis—is a rare, aggressive, and often life-threatening opportunistic fungal infection involving the paranasal sinuses, orbits, and central nervous system. Read more about Rhinocerebral phycomycosis

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About Rhinocerebral phycomycosis.

Rhinocerebral phycomycosis—more commonly termed rhinocerebral mucormycosis or zygomycosis—is a rare, aggressive, and often life-threatening opportunistic fungal infection involving the paranasal sinuses, orbits, and central nervous system.

It primarily affects immunocompromised individuals, most notably patients with uncontrolled diabetes mellitus presenting with ketoacidosis, prolonged neutropenia, hematologic malignancies, or immunosuppressive therapy.

Pathophysiologically, ubiquitous environmental molds belonging to the order Mucorales (such as *Rhizopus* and *Mucor* species) invade the nasal mucosa and demonstrate marked angioinvasion, producing vascular thrombosis, extensive tissue necrosis, and hallmark black necrotic eschars with rapid contiguous intracranial extension.

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