Indication

Severe uncontrolled hypertension

Severe uncontrolled hypertension is a cardiovascular condition defined by persistently and markedly elevated arterial pressure—typically characterized by severe systolic elevations of at least 180 mm Hg and/or diastolic elevations of at least 110 to 120 mm Hg—that remains above therapeutic targets despite active medical management or inadequate therapy. Read more about Severe uncontrolled hypertension

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About Severe uncontrolled hypertension.

Severe uncontrolled hypertension is a cardiovascular condition defined by persistently and markedly elevated arterial pressure—typically characterized by severe systolic elevations of at least 180 mm Hg and/or diastolic elevations of at least 110 to 120 mm Hg—that remains above therapeutic targets despite active medical management or inadequate therapy.

Primarily affecting the systemic vasculature, the myocardium, kidneys, and central nervous system, this state arises from heightened peripheral vascular resistance, neurohormonal dysregulation, and arterial stiffness.

If left unmitigated, the sustained hemodynamic stress overwhelms vascular autoregulation, precipitating progressive end-organ damage such as left ventricular hypertrophy, renal insufficiency, and cerebrovascular disease.

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