Synovial sarcoma

Synovial sarcoma is a rare, high-grade soft tissue malignancy of uncertain cellular differentiation that most frequently affects adolescents and young adults

Synovial sarcoma is a rare, high-grade soft tissue malignancy of uncertain cellular differentiation that most frequently affects adolescents and young adults Clinically, it often presents as an indolent or slow-growing deep mass, with a marked propensity for local recurrence and late hematogenous metastasis, most commonly to the lungs Pathophysiologically, it is defined by a characteristic reciprocal chromosomal translocation, t(X;18)(p11.2;q11.2), which results in the oncogenic *SS18-SSX* fusio...

The disease primarily develops in the deep soft tissues of the extremities—especially near large joints in the legs and arms—though it can also arise in the trunk, abdomen, lungs, and head or neck region Clinically, it often presents as an indolent or slow-growing deep mass, with a marked propensity for local recurrence and late hematogenous metastasis, most commonly to the lungs

The disease primarily develops in the deep soft tissues of the extremities—especially near large joints in the legs and arms—though it can also arise in the trunk, abdomen, lungs, and head or neck region

The disease primarily develops in the deep soft tissues of the extremities—especially near large joints in the legs and arms—though it can also arise in the trunk, abdomen, lungs, and head or neck region Clinically, it often presents as an indolent or slow-growing deep mass, with a marked propensity for local recurrence and late hematogenous metastasis, most commonly to the lungs