Indication

Ventilator-associated pneumonia due to Acinetobacter

Ventilator-associated pneumonia due to *Acinetobacter* is a severe hospital-acquired lower respiratory tract infection arising in critically ill patients undergoing invasive mechanical ventilation for 48 hours or more. Read more about Ventilator-associated pneumonia due to Acinetobacter

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About Ventilator-associated pneumonia due to Acinetobacter.

Ventilator-associated pneumonia due to *Acinetobacter* is a severe hospital-acquired lower respiratory tract infection arising in critically ill patients undergoing invasive mechanical ventilation for 48 hours or more.

It primarily affects the pulmonary parenchyma of intensive care unit populations following bacterial colonization of the airways and microaspiration around the endotracheal tube cuff.

The infection is characterized by new or progressive pulmonary infiltrates on chest imaging, fever, purulent endotracheal secretions, leukocytosis, and worsening gas exchange, with microbiological confirmation of *Acinetobacter* species (commonly the *Acinetobacter baumannii-calcoaceticus* complex) from lower respiratory tract cultures.

It frequently involves multidrug-resistant strains, presenting a high risk of treatment failure, septic shock, and in-hospital mortality.

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