Visceral leishmaniasis

Visceral leishmaniasis, also known as kala-azar, is a severe, potentially fatal systemic protozoan infection caused by species of the *Leishmania donovani* complex (principally *L. donovani* and *L. infantum*) and transmitted by the bite of infected female phlebotomine sand flies The disease primarily targets macrophages within the reticuloendothelial system, causing widespread dissemination to internal organs such as the spleen, liver, and bone marrow It classically presents with prolonged irre...

Visceral leishmaniasis, also known as kala-azar, is a severe, potentially fatal systemic protozoan infection caused by species of the *Leishmania donovani* complex (principally *L. donovani* and *L. infantum*) and transmitted by the bite of infected female phlebotomine sand flies

Visceral leishmaniasis, also known as kala-azar, is a severe, potentially fatal systemic protozoan infection caused by species of the *Leishmania donovani* complex (principally *L. donovani* and *L. infantum*) and transmitted by the bite of infected female phlebotomine sand flies It classically presents with prolonged irregular fever, significant hepatosplenomegaly, substantial weight loss or cachexia, hypergammaglobulinemia, and pancytopenia resulting from bone marrow infiltration and splenic s...

The disease primarily targets macrophages within the reticuloendothelial system, causing widespread dissemination to internal organs such as the spleen, liver, and bone marrow

It classically presents with prolonged irregular fever, significant hepatosplenomegaly, substantial weight loss or cachexia, hypergammaglobulinemia, and pancytopenia resulting from bone marrow infiltration and splenic sequestration