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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 73–84 of 1,604 articles

PubMed

Repetitive Transcranial Magnetic Stimulation in Pain Management: A Narrative Review of Randomized Controlled Trials.

Abstract Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique widely applied in clinical practice for various conditions, including pain management. Because a proportion of patients with pain remain refractory to conventional treatments and given the promising therapeutic potential and favorable safety profile of rTMS, its application in pain management warrants comprehensive evaluation. This narrative review aims to explore the application of rTMS in p...

Pain Management
Doan HN, Kwak S, Moon JS, Park WT, Baek J, Chang MC•
PubMed

Drinking Status and Mental Health Symptoms Among First-Year Medical Students: A Cross-Sectional Chain Mediation Analysis of Health-Promoting Lifestyle and Sleep Quality.

Purpose The high prevalence of mental health symptoms among college students is a global public concern. However, the research on potential risk factors such as drinking remains insufficient. This study aimed to explore the association between drinking and mental health among college students, and examine the mediating roles of health-promoting lifestyle (HPL) and sleep quality. Methods A single-center cross-sectional survey was conducted among 2272 first-year students from a medical universi...

Mental Health
Shi C, Wang Z, Luo J, Zhao M•
PubMed

RhinAsthma Patient Perspective: Cross-Cultural Adaptation and Validation of a Brief Rhinitis and Asthma Quality-of-Life Measure in Chinese Adults.

Background Combined allergic rhinitis and asthma syndrome (CARAS) impairs health-related quality of life (HRQoL). The 8-item RhinAsthma Patient Perspective (RAPP) measures their combined impact. We translated and culturally adapted the RAPP for China and evaluated its psychometric properties. Methods Following International Society for Pharmacoeconomics and Outcomes Research principles, the RAPP was translated from Italian into simplified Chinese and cognitively debriefed. Psychometric evalua...

Asthma
Zhang P, Zhang Y, Hu Y, Baiardini I, Braido F, Wang J, Chen T, Xie Y•
PubMed

Procalcitonin as a Stewardship Checkpoint, Not an Antibiotic Gatekeeper: From Antibiotic Initiation to Discontinuation in Resource-Limited Hospitals.

Abstract Procalcitonin has emerged as a promising biomarker for antimicrobial stewardship; however, its clinical value differs substantially across the antibiotic treatment pathways. Evidence supporting its use to determine whether antibiotics should be initiated remains limited, particularly in patients with suspected sepsis or physiological instability, in whom a low initial concentration cannot safely exclude serious bacterial infections. Its more consistent value appears after empirical tre...

Antibiotic
Abdi DA, Yusuf AA, Hirsi AM, Hassan AM, Mohamed AA, Ulusow KH, Abdulle AH, Ahmed MM•
PubMed

Measurement Properties of Spanish Versions of Two Exercise Self-Efficacy Scales in People with Multiple Sclerosis.

Background Regular physical activity (PA) is recommended for people with multiple sclerosis (PwMS), yet long-term exercise adherence remains suboptimal. Exercise self-efficacy is a key patient-reported determinant of exercise initiation and maintenance, making its assessment relevant for both clinical practice and research. Although the Exercise Self-Efficacy Scale (EXSE; McAuley et al 1993) and the Exercise Self-Efficacy (ESE; Neupert et al 2009) have been previously used, validated Spanish ve...

Scales
Santoyo-Medina C, Janer M, Lidón-Moyano C, Meza-Murillo ER, Galán I, Montalban X, Bagur-Calafat C, Sastre-Garriga J, Amor-Barbosa M•
PubMed

Pregnancy-Induced Hypertension Complicated by Posterior Reversible Encephalopathy Syndrome: A Case Series of Two Patients.

ABSTRACT Posterior reversible encephalopathy syndrome (PRES) is a rare but potentially life‐threatening neurological complication associated with hypertensive disorders of pregnancy. This report presents two cases of pregnancy‐induced hypertension complicated by PRES, both clinically characterized by headache and visual disturbances, with characteristic neuroimaging findings. The clinical manifestations, laboratory findings, and magnetic resonance imaging (MRI) characteristics of two patients a...

Pregnancy
Zhao X, Yan M, Long F, Mumdzjans A, Song R•
PubMed

Unexplained Optic Neuritis and New Heart Block: A Diagnostically Challenging Case of Probable Sarcoidosis.

ABSTRACT Sarcoidosis is a systemic inflammatory disease of unknown etiology and manifests in multiple forms. It can affect several organs within the body; however, the lungs and intra‐thoracic lymph nodes are involved in the majority of cases. Diagnosis can be challenging due to the diversity of presentation and similarities to other systemic diseases. Although biopsy is often used to confirm the diagnosis, areas of disease involvement can be difficult to access. This case involves a patient wi...

Sarcoidosis
Kamath C, Al-Qaysi G, Paudel H, Saado J, Nwaonu J•
PubMed

Bone marrow sarcoidosis in Takayasu arteritis: Case report and literature review.

Rationale: Takayasu arteritis (TA) is a systemic granulomatous large-vessel vasculitis predominantly involving the aorta and its primary branches. Sarcoidosis is a systemic granulomatous disorder characterized histologically by non-necrotizing epithelioid granulomas, most commonly affecting the lungs. Although the coexistence of TA and sarcoidosis has been documented, bone marrow involvement by sarcoidosis in a patient with concomitant TA has not, to our knowledge, been previously reported. Pa...

Sarcoidosis
Fakih O, Hachem S, Chamas R, Abi Dargham S, Aitisha Tabesh O, Fayad F•
PubMed

Toward Immersive Diabetes Education: Understanding User Needs for Virtual Reality-Assisted Self-Management Support in Adults With Type 2 Diabetes Mellitus.

Effective self‐management in Type 2 diabetes mellitus (T2DM) requires sustained adherence to diet, physical activity, medication, and lifestyle modification. However, conventional diabetes education often remains generic, one‐directional, and insufficiently responsive to the psychological, behavioral, and contextual challenges patients face in daily life. Immersive technologies such as virtual reality (VR) may offer a more engaging approach to diabetes education, yet evidence on the user needs t...

Type 2 Diabetes Mellitus
Jafar N, Setyawati A, Ibeneme SC, Akbar A, Ahmad HH, Suriani S•
PubMed

Pathological Ossification of Spinal Ligament-Derived Fibroblasts in an Inflammatory Micro-Environment via Activation of the ECM/ITGA5/FAK/AKT Pathway in Ankylosing Spondylitis.

ABSTRACT Chronic inflammation and heterotopic ossification (HO) were typical hallmarks of ankylosing spondylitis (AS). Although existing target inflammation inhibitors could reduce inflammation but failed to halt HO progression, highlighting the need for osteogenesis‐specific treatments. However, the role of fibroblasts (Fbs) responsible for extracellular matrix (ECM) remodelling in AS‐associated pathological ossification remained unclear. In this study, osteogenic capacity, pathological condit...

Ankylosing Spondylitis
Qiao M, Wang KY, Song CY, Lu JS, Li JK, Qiu Y, Qian BP, Zhu ZZ•
PubMed

Evaluation of the efficacy of Si-based agent in Rheumatoid Arthritis with complicating vestibular impairment.

Background Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent joint inflammation and progressive disability. Although current therapies have improved clinical outcomes, safer and more effective therapeutic approaches remain needed. Silicon (Si)-based agents have antioxidant and anti-inflammatory properties and have shown beneficial effects in several inflammatory disease models. Methods We evaluated the effects of oral administration of a Si-based agent in a...

Rheumatoid Arthritis
Harada S, Koyama Y, Kobayashi Y, Imai T, Yoshioka Y, Kobayashi H, Inohara H, Shimada S•
PubMed

Deep learning optimisation for cardiology: Neural Architecture Search-driven arrhythmia classification with electrocardiograms.

Cardiovascular disease is the leading cause of death worldwide. Sudden cardiac death (SCD) accounts for roughly 50% of all cardiac deaths. The electrocardiogram (ECG) is widely used for diagnosing cardiac disease. However, the complexity of interpretation limits the ECG’s efficacy. Modern deep learning methods can assist clinicians in diagnosis. We applied Neural Architecture Search (NAS) to identify optimal deep learning architectures for classifying cardiac arrhythmias with ECGs. We applied th...

Cardiology
Vanegas Müller E, Joe-Oshodi A, Banerjee A, Villarroel M•

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