Protopam Chloride (pralidoxime chloride)
Organophosphate Poisoning Antidote Injection Vial (Ea)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Generic name: pralidoxime chloride
Drug class: Organophosphate Poisoning Antidote
Therapeutic class: Antidotes and other Reversal Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Protopam Chloride
Indications
The following indications are listed for Protopam Chloride:
- Cholinesterase Inhibitors Toxicity
- Organophos Insecticide Poisoning
- Organophosphorous Overdose
- Poisoning Due To Nerve Agent
Also known as: Anticholinesterase Agent Poisoning, Organophosphate Poisoning, Poisoning By War Nerve Agent.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
- Hypertension
- Kidney disease with reduction in glomerular filtration rate (GFr)
Adverse reactions
There is no enhanced messaging for this drug.
More Frequent
- Blurred vision
- Diplopia
- Dizziness
- Hypertension
- Hyperventilation
- Injection site sequelae
- Laryngismus
- Muscle rigidity
- Muscle weakness
- Reduced visual acuity
- Tachycardia
Less Frequent
- Increased alanine transaminase
- Increased aspartate transaminase
- Kidney disease with reduction in glomerular filtration rate (GFr)
More Frequent
- Drowsy
- Headache disorder
- Increased creatine kinase level
- Nausea
Less Frequent
- Abnormal hepatic function tests
- Accommodation disorder
- Dry skin
- Excitement
- Manic disorder
- Skin rash
- Vomiting
- Xerostomia
Precautions
No enhanced messaging available.
No enhanced messaging available.
Safe use of pralidoxime during pregnancy has not been established.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Cholinesterase inhibitors toxicity | ||
| T44.0x1A | ICD10CM | Poisoning by anticholinesterase agents, accidental (unintentional), initial encounter |
| T44.0x2A | ICD10CM | Poisoning by anticholinesterase agents, intentional self-harm, initial encounter |
| T44.0x3A | ICD10CM | Poisoning by anticholinesterase agents, assault, initial encounter |
| T44.0x4A | ICD10CM | Poisoning by anticholinesterase agents, undetermined, initial encounter |
| Organophos insecticide poisoning | ||
| T60.0 | ICD10CM | Toxic effect of organophosphate and carbamate insecticides |
| T60.0x | ICD10CM | Toxic effect of organophosphate and carbamate insecticides |
| T60.0x1 | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, accidental (unintentional) |
| T60.0x1A | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, accidental (unintentional), initial encounter |
| T60.0x2 | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, intentional self-harm |
| T60.0x2A | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, intentional self-harm, initial encounter |
| T60.0x3 | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, assault |
| T60.0x3A | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, assault, initial encounter |
| T60.0x4 | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, undetermined |
| T60.0x4A | ICD10CM | Toxic effect of organophosphate and carbamate insecticides, undetermined, initial encounter |
| Organophosphorous overdose | ||
| T44.0x1A | ICD10CM | Poisoning by anticholinesterase agents, accidental (unintentional), initial encounter |
| T44.0x2A | ICD10CM | Poisoning by anticholinesterase agents, intentional self-harm, initial encounter |
| T44.0x3A | ICD10CM | Poisoning by anticholinesterase agents, assault, initial encounter |
| T44.0x4A | ICD10CM | Poisoning by anticholinesterase agents, undetermined, initial encounter |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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