Drug class
5 Fluoropyrimidines
The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine. Read more about 5 Fluoropyrimidines
34 drugs in this class 34 manufacturers
Drugs in 5 Fluoropyrimidines
CAPECITABINE
CAPECITABINE
FLUOROURACIL
FLUOROURACIL
FLUOROURACIL
FAVLYXA (fluorouracil)
The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine.
They exert their therapeutic anticancer effect predominantly by inhibiting thymidylate synthase and misincorporating fraudulent fluorinated metabolites into RNA and DNA, thereby disrupting nucleic acid synthesis and triggering cell death.
In clinical oncology, this class serves as a foundational therapeutic backbone for treating various solid tumors, most notably gastrointestinal malignancies including colorectal, gastric, and pancreatic cancers, as well as breast cancer and select hyperproliferative skin conditions.
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fda.gov
The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine In clinical oncology, this class serves as a foundational therapeutic backbone for treating various solid tumors, most notably gastrointestinal malignancies including colorectal, gastric, and pancreatic cancers, as well as breast cancer and select hyperproliferative skin conditions
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cancer.gov
The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine
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cancer.gov
They exert their therapeutic anticancer effect predominantly by inhibiting thymidylate synthase and misincorporating fraudulent fluorinated metabolites into RNA and DNA, thereby disrupting nucleic acid synthesis and triggering cell death
-
nih.gov
They exert their therapeutic anticancer effect predominantly by inhibiting thymidylate synthase and misincorporating fraudulent fluorinated metabolites into RNA and DNA, thereby disrupting nucleic acid synthesis and triggering cell death
-
mydruggenome.org
In clinical oncology, this class serves as a foundational therapeutic backbone for treating various solid tumors, most notably gastrointestinal malignancies including colorectal, gastric, and pancreatic cancers, as well as breast cancer and select hyperproliferative skin conditions
-
nih.gov
In clinical oncology, this class serves as a foundational therapeutic backbone for treating various solid tumors, most notably gastrointestinal malignancies including colorectal, gastric, and pancreatic cancers, as well as breast cancer and select hyperproliferative skin conditions
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