Drug class

5 Fluoropyrimidines

The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine. Read more about 5 Fluoropyrimidines

34 drugs in this class 34 manufacturers

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Drugs in 5 Fluoropyrimidines

Showing 28–34 of 34 drugs

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
CIVICASCRIPT, L

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
MYLAN INSTITUTI

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
BLUEPOINT/ONCOP

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
XIROMED, LLC

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
FRESENIUS KABI

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
FRESENIUS KABI
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About 5 Fluoropyrimidines.

The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine.

They exert their therapeutic anticancer effect predominantly by inhibiting thymidylate synthase and misincorporating fraudulent fluorinated metabolites into RNA and DNA, thereby disrupting nucleic acid synthesis and triggering cell death.

In clinical oncology, this class serves as a foundational therapeutic backbone for treating various solid tumors, most notably gastrointestinal malignancies including colorectal, gastric, and pancreatic cancers, as well as breast cancer and select hyperproliferative skin conditions.