Drug class

Aminoglycosides, Parenteral

Parenteral aminoglycosides are a class of potent, intravenously or intramuscularly administered antibacterial agents—primarily including gentamicin, tobramycin, and amikacin—used for systemic therapy. Read more about Aminoglycosides, Parenteral

31 drugs in this class 23 manufacturers

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Drugs in Aminoglycosides, Parenteral

Showing 10–18 of 31 drugs

AMIKACIN SULFATE

AMINOGLYCOSIDES, PARENTERAL · STAPHYLOCOCCAL SEPTICEMIA ·+60
Hikma Pharmaceuticals USA

TOBRAMYCIN SULFATE

AMINOGLYCOSIDES, PARENTERAL · E. COLI SEPTICEMIA ·+44
NORTHSTAR RX LL

GENTAMICIN SULFATE

AMINOGLYCOSIDES, PARENTERAL · SEPSIS CAUSED BY ENTEROBACTER ·+63
EUGIA US LLC

TOBRAMYCIN SULFATE

AMINOGLYCOSIDES, PARENTERAL · E. COLI SEPTICEMIA ·+44
SLATE RUN PHARM
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About Aminoglycosides, Parenteral.

Parenteral aminoglycosides are a class of potent, intravenously or intramuscularly administered antibacterial agents—primarily including gentamicin, tobramycin, and amikacin—used for systemic therapy.

They exert concentration-dependent bactericidal action by crossing bacterial membranes and binding irreversibly to the 30S ribosomal subunit, which disrupts mRNA translation, causes mistranslation of proteins, and compromises the integrity of the bacterial cell envelope.

Clinically, these parenteral formulations serve as vital therapeutic options for severe, life-threatening systemic infections, including sepsis, complicated intra-abdominal infections, complicated urinary tract infections, hospital-acquired pneumonia, and infective endocarditis, predominantly targeting aerobic Gram-negative bacilli or working synergistically against select Gram-positive pathogens.