Antiarrhythmic - Class IA

Antiarrhythmics – Class IA are a subclass of Vaughan-Williams Class I antiarrhythmic medications that act as intermediate-potency fast sodium channel blockers

Antiarrhythmics – Class IA are a subclass of Vaughan-Williams Class I antiarrhythmic medications that act as intermediate-potency fast sodium channel blockers By moderately inhibiting phase 0 depolarization and concurrently blocking outward potassium channels, they slow cardiac conduction velocity, lengthen the action potential duration, and prolong the effective refractory period

By moderately inhibiting phase 0 depolarization and concurrently blocking outward potassium channels, they slow cardiac conduction velocity, lengthen the action potential duration, and prolong the effective refractory period Common representatives of this pharmacologic class include quinidine, procainamide, and disopyramide

Clinically, these agents are utilized to suppress and manage a spectrum of supraventricular and ventricular arrhythmias, including atrial fibrillation, atrial flutter, and ventricular tachycardia Common representatives of this pharmacologic class include quinidine, procainamide, and disopyramide