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Anticonvulsant - GABA Modulators

Anticonvulsant GABA modulators constitute a pharmacologic class of antiseizure medications that suppress central nervous system neuronal hyperexcitability by augmenting gamma-aminobutyric acid–mediated inhibitory signaling. Read more about Anticonvulsant - GABA Modulators

18 drugs in this class 17 manufacturers

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Showing 1–9 of 18 drugs

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SABRIL (vigabatrin)

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

LUNDBECK INC.

SABRIL (vigabatrin)

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

LUNDBECK INC.

TIAGABINE HCL

ANTICONVULSANTS · PARTIAL EPILEPSY TREATMENT ADJUNCT

SUN PHARMACEUTI

VIGABATRIN

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

PAR HEALTH USA,

VIGABATRIN

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

Amneal Pharmaceuticals

VIGABATRIN

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

Actavis Pharma

VIGADRONE (vigabatrin)

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

Upsher-Smith Laboratories

VIGABATRIN

ANTICONVULSANTS · COMPLEX-PARTIAL EPILEPSY ·+1

DR.REDDY'S LAB

ZTALMY (ganaxolone)

ANTICONVULSANTS · SEIZURES ASSOCIATED WITH CYCLIN-DEPENDENT KINASE-LIKE 5 DEFICIENCY DISORDER

MARINUS PHARMAC

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About Anticonvulsant - GABA Modulators.

Anticonvulsant GABA modulators constitute a pharmacologic class of antiseizure medications that suppress central nervous system neuronal hyperexcitability by augmenting gamma-aminobutyric acid–mediated inhibitory signaling.

These agents primarily function as positive allosteric modulators of postsynaptic GABAA receptors—increasing receptor affinity, opening frequency, or chloride channel open duration—or by elevating synaptic GABA levels through the inhibition of its reuptake or enzymatic degradation.

The resulting chloride influx hyperpolarizes the neuronal membrane, stabilizing the resting potential and dampening seizure propagation.

Clinically, medications within this class are utilized across diverse neurological indications, predominantly in the management of focal and generalized epilepsy, acute seizure clusters, and status epilepticus.

nih.gov
Anticonvulsant GABA modulators constitute a pharmacologic class of antiseizure medications that suppress central nervous system neuronal hyperexcitability by augmenting gamma-aminobutyric acid–mediated inhibitory signaling
epilepsysociety.org.uk
Anticonvulsant GABA modulators constitute a pharmacologic class of antiseizure medications that suppress central nervous system neuronal hyperexcitability by augmenting gamma-aminobutyric acid–mediated inhibitory signaling
drugbank.com
These agents primarily function as positive allosteric modulators of postsynaptic GABAA receptors—increasing receptor affinity, opening frequency, or chloride channel open duration—or by elevating synaptic GABA levels through the inhibition of its reuptake or enzymatic degradation The resulting chloride influx hyperpolarizes the neuronal membrane, stabilizing the resting potential and dampening seizure propagation
nih.gov
These agents primarily function as positive allosteric modulators of postsynaptic GABAA receptors—increasing receptor affinity, opening frequency, or chloride channel open duration—or by elevating synaptic GABA levels through the inhibition of its reuptake or enzymatic degradation
patsnap.com
These agents primarily function as positive allosteric modulators of postsynaptic GABAA receptors—increasing receptor affinity, opening frequency, or chloride channel open duration—or by elevating synaptic GABA levels through the inhibition of its reuptake or enzymatic degradation The resulting chloride influx hyperpolarizes the neuronal membrane, stabilizing the resting potential and dampening seizure propagation
nih.gov
These agents primarily function as positive allosteric modulators of postsynaptic GABAA receptors—increasing receptor affinity, opening frequency, or chloride channel open duration—or by elevating synaptic GABA levels through the inhibition of its reuptake or enzymatic degradation Clinically, medications within this class are utilized across diverse neurological indications, predominantly in the management of focal and generalized epilepsy, acute seizure clusters, and status epilepticus
nih.gov
Clinically, medications within this class are utilized across diverse neurological indications, predominantly in the management of focal and generalized epilepsy, acute seizure clusters, and status epilepticus