Drug class

Antidiuretic Hormone Antagonists

Antidiuretic hormone antagonists, commonly known as vasopressin receptor antagonists or vaptans, are a pharmacologic class of agents that inhibit the effects of arginine vasopressin on its target receptors. Read more about Antidiuretic Hormone Antagonists

20 drugs in this class 16 manufacturers

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Drugs in Antidiuretic Hormone Antagonists

Showing 19–20 of 20 drugs

TOLVAPTAN

ANTIDIURETIC HORMONE ANTAGONISTS · SIADH SYNDROME ·+1
NORTHSTAR RX LL

TOLVAPTAN

ANTIDIURETIC HORMONE ANTAGONISTS · AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
TEVA PHARM
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About Antidiuretic Hormone Antagonists.

Antidiuretic hormone antagonists, commonly known as vasopressin receptor antagonists or vaptans, are a pharmacologic class of agents that inhibit the effects of arginine vasopressin on its target receptors.

By primarily blocking vasopressin V2 receptors in the renal collecting ducts, these drugs prevent water reabsorption and promote aquaresis—the selective excretion of solute-free water without substantial electrolyte loss.

They are clinically utilized to manage euvolemic and hypervolemic hyponatremia associated with conditions such as heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion, as well as to slow kidney function decline and cyst development in rapidly progressing autosomal dominant polycystic kidney disease.