Antidiuretic Hormone

The therapeutic class commonly referred to as antidiuretic hormones, or vasopressin receptor agonists, comprises exogenous peptide formulations and synthetic analogues of endogenous arginine vasopressin These agents function primarily by binding to renal V2 receptors in the collecting duct to promote aquaporin-mediated water reabsorption, while certain agents also stimulate vascular V1 receptors to induce peripheral vasoconstriction

The therapeutic class commonly referred to as antidiuretic hormones, or vasopressin receptor agonists, comprises exogenous peptide formulations and synthetic analogues of endogenous arginine vasopressin

These agents function primarily by binding to renal V2 receptors in the collecting duct to promote aquaporin-mediated water reabsorption, while certain agents also stimulate vascular V1 receptors to induce peripheral vasoconstriction Clinically, medications in this class are indicated to control polyuria and polydipsia in central diabetes insipidus, increase systemic vascular resistance during vasodilatory shock, manage nocturnal enuresis, and support hemostasis in conditions such as mild hemoph...

Clinically, medications in this class are indicated to control polyuria and polydipsia in central diabetes insipidus, increase systemic vascular resistance during vasodilatory shock, manage nocturnal enuresis, and support hemostasis in conditions such as mild hemophilia A and von Willebrand disease