ERIVEDGE (vismodegib)
ANTINEOPLASTIC - HEDGEHOG PATHWAY INHIBITORS · BASAL CELL CARCINOMA OF SKIN
GENENTECH
Drug class
Antineoplastic - Hedgehog Pathway Inhibitors
Antineoplastic Hedgehog pathway inhibitors are a targeted class of anticancer agents designed to disrupt aberrant Hedgehog signaling cascades involved in cellular proliferation, survival, and stem-cell maintenance. Read more about Antineoplastic - Hedgehog Pathway Inhibitors
4 drugs in this class 4 manufacturers
Drugs in Antineoplastic - Hedgehog Pathway Inhibitors
ODOMZO (sonidegib phosphate)
ANTINEOPLASTIC - HEDGEHOG PATHWAY INHIBITORS · BASAL CELL CARCINOMA OF SKIN
Novartis Pharmaceuticals
ODOMZO (sonidegib phosphate)
ANTINEOPLASTIC - HEDGEHOG PATHWAY INHIBITORS · BASAL CELL CARCINOMA OF SKIN
SUN PHARMA GLOB
DAURISMO (glasdegib maleate)
ANTINEOPLASTIC - HEDGEHOG PATHWAY INHIBITORS · ACUTE MYELOID LEUKEMIA
Parke-Davis Pfizer
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Antineoplastic Hedgehog pathway inhibitors are a targeted class of anticancer agents designed to disrupt aberrant Hedgehog signaling cascades involved in cellular proliferation, survival, and stem-cell maintenance.
These small-molecule therapies primarily function by binding to and inhibiting Smoothened, a pivotal transmembrane protein receptor, thereby blocking downstream transcription factors and halting oncogenic signal transmission.
Clinically, members of this class—such as vismodegib and sonidegib—are indicated for the treatment of advanced, recurrent, or metastatic basal cell carcinoma when surgical resection or radiation is unfeasible, while other agents like glasdegib are utilized in combination regimens for newly diagnosed acute myeloid leukemia.
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drugs.com
Antineoplastic Hedgehog pathway inhibitors are a targeted class of anticancer agents designed to disrupt aberrant Hedgehog signaling cascades involved in cellular proliferation, survival, and stem-cell maintenance
-
nih.gov
Antineoplastic Hedgehog pathway inhibitors are a targeted class of anticancer agents designed to disrupt aberrant Hedgehog signaling cascades involved in cellular proliferation, survival, and stem-cell maintenance
-
nih.gov
These small-molecule therapies primarily function by binding to and inhibiting Smoothened, a pivotal transmembrane protein receptor, thereby blocking downstream transcription factors and halting oncogenic signal transmission
-
nih.gov
These small-molecule therapies primarily function by binding to and inhibiting Smoothened, a pivotal transmembrane protein receptor, thereby blocking downstream transcription factors and halting oncogenic signal transmission
-
nih.gov
Clinically, members of this class—such as vismodegib and sonidegib—are indicated for the treatment of advanced, recurrent, or metastatic basal cell carcinoma when surgical resection or radiation is unfeasible, while other agents like glasdegib are utilized in combination regimens for newly diagnosed acute myeloid leukemia
-
aml-hub.com
Clinically, members of this class—such as vismodegib and sonidegib—are indicated for the treatment of advanced, recurrent, or metastatic basal cell carcinoma when surgical resection or radiation is unfeasible, while other agents like glasdegib are utilized in combination regimens for newly diagnosed acute myeloid leukemia
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