Drug class

Antitussives

Antitussives are a recognized therapeutic class of pharmacological agents, commonly referred to as cough suppressants, designed to inhibit or reduce the frequency and intensity of coughing. Read more about Antitussives

1,140 drugs in this class 157 manufacturers

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Drugs in Antitussives

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About Antitussives.

Antitussives are a recognized therapeutic class of pharmacological agents, commonly referred to as cough suppressants, designed to inhibit or reduce the frequency and intensity of coughing.

They primarily exert their effect centrally by depressing the cough center in the medulla and brainstem—exemplified by agents such as dextromethorphan, codeine, and hydrocodone—or peripherally by anesthetizing stretch receptors located within the respiratory tract, as seen with benzonatate.

Clinically, antitussives provide short-term, symptomatic relief for nonproductive or bothersome coughs associated with acute upper respiratory tract infections, common colds, environmental allergies, bronchitis, and other acute or chronic inflammatory conditions of the respiratory tree.