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Drug class

Antiviral-HIV (Antiretroviral) Nonnucleoside RT Inhibitor

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) constitute an essential class of antiretroviral medications utilized primarily for the management and treatment of human immunodeficiency virus type 1 (HIV-1) infection. Read more about Antiviral-HIV (Antiretroviral) Nonnucleoside RT Inhibitor

46 drugs in this class 24 manufacturers

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JULUCA (dolutegravir sodium/rilpivirine HCl)

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

VIIV HEALTHCARE

EFAVIRENZ

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

CAMBER PHARMACE

EFAVIRENZ

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

STRIDES PHARMA

SYMFI LO (efavirenz/lamivudine/tenofovir disoproxil fumarate)

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

DEY LABS.

SYMFI (efavirenz/lamivudine/tenofovir disoproxil fumarate)

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

DEY LABS.

NEVIRAPINE

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

AUROBINDO PHARM

NEVIRAPINE ER (nevirapine)

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

MACLEODS PHARMA

EFAVIRENZ

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

AUROBINDO PHARM

EFAVIRENZ

ANTIVIRAL-HIV (ANTIRETROVIRAL) NONNUCLEOSIDE RT INHIBITOR · HIV INFECTION

CIPLA USA, INC.

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About Antiviral-HIV (Antiretroviral) Nonnucleoside RT Inhibitor.

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) constitute an essential class of antiretroviral medications utilized primarily for the management and treatment of human immunodeficiency virus type 1 (HIV-1) infection.

They function through non-competitive, allosteric binding to an allosteric pocket adjacent to the active catalytic site of the HIV-1 reverse transcriptase enzyme.

This binding induces a conformational change that arrests enzyme activity, halting the reverse transcription of viral single-stranded RNA into double-stranded proviral DNA and preventing viral replication within host immune cells.

Clinically, these agents—such as efavirenz, rilpivirine, etravirine, and doravirine—serve as critical components of combination antiretroviral therapy (cART) regimens to achieve sustained virologic suppression and preserve immune function.

nih.gov
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) constitute an essential class of antiretroviral medications utilized primarily for the management and treatment of human immunodeficiency virus type 1 (HIV-1) infection
nih.gov
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) constitute an essential class of antiretroviral medications utilized primarily for the management and treatment of human immunodeficiency virus type 1 (HIV-1) infection This binding induces a conformational change that arrests enzyme activity, halting the reverse transcription of viral single-stranded RNA into double-stranded proviral DNA and preventing viral replication within host immune cells
fda.gov
They function through non-competitive, allosteric binding to an allosteric pocket adjacent to the active catalytic site of the HIV-1 reverse transcriptase enzyme
nih.gov
They function through non-competitive, allosteric binding to an allosteric pocket adjacent to the active catalytic site of the HIV-1 reverse transcriptase enzyme Clinically, these agents—such as efavirenz, rilpivirine, etravirine, and doravirine—serve as critical components of combination antiretroviral therapy (cART) regimens to achieve sustained virologic suppression and preserve immune function
hiv.gov
This binding induces a conformational change that arrests enzyme activity, halting the reverse transcription of viral single-stranded RNA into double-stranded proviral DNA and preventing viral replication within host immune cells
iapac.org
This binding induces a conformational change that arrests enzyme activity, halting the reverse transcription of viral single-stranded RNA into double-stranded proviral DNA and preventing viral replication within host immune cells Clinically, these agents—such as efavirenz, rilpivirine, etravirine, and doravirine—serve as critical components of combination antiretroviral therapy (cART) regimens to achieve sustained virologic suppression and preserve immune function
hivguidelines.org
Clinically, these agents—such as efavirenz, rilpivirine, etravirine, and doravirine—serve as critical components of combination antiretroviral therapy (cART) regimens to achieve sustained virologic suppression and preserve immune function