Drug class

Bisphosphonates

Bisphosphonates are a therapeutic class of antiresorptive medications structurally analogous to inorganic pyrophosphate that bind directly to hydroxyapatite crystals in the bone matrix. Read more about Bisphosphonates

73 drugs in this class 47 manufacturers

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Drugs in Bisphosphonates

Showing 64–72 of 73 drugs

ZOLEDRONIC ACID

HYPERCALCEMIA AGENTS · HUMORAL HYPERCALCEMIA OF MALIGNANCY ·+2
AVENACY, INC

ZOLEDRONIC ACID

HYPERCALCEMIA AGENTS · HUMORAL HYPERCALCEMIA OF MALIGNANCY ·+2
Avet Pharmaceuticals

ZOLEDRONIC ACID

HYPERCALCEMIA AGENTS · HUMORAL HYPERCALCEMIA OF MALIGNANCY ·+2
DR. REDDY'S/NOV

ZOLEDRONIC ACID

HYPERCALCEMIA AGENTS · HUMORAL HYPERCALCEMIA OF MALIGNANCY ·+2
DR. REDDY'S/PRE

ALENDRONATE SODIUM

OSTEOPOROSIS AGENTS · POSTMENOPAUSAL OSTEOPOROSIS ·+1
Hikma Pharmaceuticals USA

ALENDRONATE SODIUM

OSTEOPOROSIS AGENTS · POSTMENOPAUSAL OSTEOPOROSIS ·+1
NOVITIUM/ANI PH

RISEDRONATE SODIUM

OSTEOPOROSIS AGENTS · POSTMENOPAUSAL OSTEOPOROSIS ·+2
GREENSTONE-MYLA

IBANDRONATE SODIUM

OSTEOPOROSIS AGENTS · POSTMENOPAUSAL OSTEOPOROSIS ·+1
A-S MEDICATION
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About Bisphosphonates.

Bisphosphonates are a therapeutic class of antiresorptive medications structurally analogous to inorganic pyrophosphate that bind directly to hydroxyapatite crystals in the bone matrix.

They exert their therapeutic effects primarily by inhibiting osteoclast-mediated bone resorption and accelerating osteoclast apoptosis, with newer nitrogen-containing agents specifically inhibiting farnesyl pyrophosphate synthase in the mevalonate pathway.

Clinically, bisphosphonates are indicated for metabolic and oncologic skeletal disorders characterized by excessive bone turnover, notably postmenopausal and glucocorticoid-induced osteoporosis, Paget disease of bone, hypercalcemia of malignancy, and solid tumor or multiple myeloma bone metastases.